Whole Brain Radiation Therapy With Standard Temozolomide Chemo-Radiotherapy and Plerixafor in Treating Patients With Glioblastoma
This phase II trial studies how well whole brain radiation therapy works with standard
temozolomide chemo-radiotherapy and plerixafor in treating patients with glioblastoma (brain
tumor). Radiation therapy uses high energy x-rays to kill tumor cells and shrink tumors.
Drugs used in chemotherapy, such as temozolomide, work in different ways to stop the growth
of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping
them from spreading. Plerixafor is a drug that may prevent recurrence of glioblastoma after
radiation treatment. Giving whole brain radiation therapy with standard temozolomide
chemo-radiotherapy...
