Phase III Study of Rindopepimut/GM-CSF in Patients With Newly Diagnosed Glioblastoma
Study Purpose
This 2-arm, randomized, phase III study will investigate the efficacy and safety of the addition of rindopepimut (an experimental cancer vaccine that may act to promote anti-cancer effects in patients who have tumors that express the EGFRvIII protein) to the current standard of care (temozolomide) in patients with recently diagnosed glioblastoma, a type of brain cancer. All patients will be administered temozolomide, the standard treatment for glioblastoma. Half the patients will be randomly assigned to receive rindopepimut and half the patients will be randomly assigned to receive a control called keyhole limpet hemocyanin. Patients will be treated in a blinded fashion (neither the patient or the doctor will know which arm of the study the patient is on). Patients will be treated until disease progression or intolerance to therapy and all patients will be followed for survival.
Recruitment Criteria
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Accepts Healthy Volunteers
Healthy volunteers are participants who do not have a disease or condition, or related conditions or symptoms |
No |
|
Study Type
An interventional clinical study is where participants are assigned to receive one or more interventions (or no intervention) so that researchers can evaluate the effects of the interventions on biomedical or health-related outcomes. An observational clinical study is where participants identified as belonging to study groups are assessed for biomedical or health outcomes. Searching Both is inclusive of interventional and observational studies. |
Interventional |
| Eligible Ages | 18 Years and Over |
| Gender | All |
Inclusion Criteria- Among other criteria, patients must meet the following conditions to be eligible for the study: 1. Adult patients, ≥ 18 years old. 2. Newly diagnosed glioblastoma. 3. Attempted surgical resection followed by conventional chemoradiation. 4. Documented EGFRvIII positive tumor status by a Sponsor designated laboratory. 5. No evidence of progressive disease from the post-operative period to the post-chemoradiation period. 6. Candidate for, and agrees to receive, adjuvant (maintenance) temozolomide therapy. 7. Systemic corticosteroid therapy at ≤2 mg of dexamethasone or equivalent per day for at least 3 days prior to randomization. 8. WHO-ECOG Performance Status ≤ 2. 9. Patients of childbearing/reproductive potential will be instructed to use birth control as defined by your doctor. Exclusion Criteria- Among other criteria, patients who meet the following conditions are NOT eligible for the study: 1. Stereotactic biopsy only (without further surgical resection) 2. Presence of diffuse leptomeningeal disease, gliomatosis cerebri, or infratentorial disease. 3. History, presence, or suspicion of metastatic disease. 4. Patients who have received any additional treatment for glioblastoma, aside from surgical resection and chemoradiation with temozolomide. 5. Active systemic infection requiring treatment. 6. History of any malignancy (other than glioblastoma) during the last three years except non-melanoma skin cancer, in situ cervical cancer, treated superficial bladder cancer, cured, early-stage prostate cancer in a patient with PSA level less than ULN,or other carcinoma in situ that has been adequately treated and cured. 7. Planned major surgery. 8. Evidence of current drug or alcohol abuse. 9. Known allergy or hypersensitivity to keyhole limpet hemocyanin (KLH), GM-CSF (sargramostim; LEUKINE®), polysorbate 80 or yeast derived products, or a history of anaphylactic reactions to shellfish proteins. 10. Severe acute or chronic medical or psychiatric condition or laboratory abnormality that could increase the risk associated with participating in a clinical trial. 11. Women who are pregnant or lactating
Trial Details
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Trial ID:
This trial id was obtained from ClinicalTrials.gov, a service of the U.S. National Institutes of Health, providing information on publicly and privately supported clinical studies of human participants with locations in all 50 States and in 196 countries. |
NCT01480479 |
|
Phase
Phase 1: Studies that emphasize safety and how the drug is metabolized and excreted in humans. Phase 2: Studies that gather preliminary data on effectiveness (whether the drug works in people who have a certain disease or condition) and additional safety data. Phase 3: Studies that gather more information about safety and effectiveness by studying different populations and different dosages and by using the drug in combination with other drugs. Phase 4: Studies occurring after FDA has approved a drug for marketing, efficacy, or optimal use. |
Phase 3 |
|
Lead Sponsor
The sponsor is the organization or person who oversees the clinical study and is responsible for analyzing the study data. |
Celldex Therapeutics |
|
Principal Investigator
The person who is responsible for the scientific and technical direction of the entire clinical study. |
N/A |
| Principal Investigator Affiliation | N/A |
|
Agency Class
Category of organization(s) involved as sponsor (and collaborator) supporting the trial. |
Industry |
| Overall Status | Completed |
| Countries | Australia, Austria, Belgium, Brazil, Canada, Colombia, Czechia, France, Germany, Greece, Hungary, India, Israel, Italy, Mexico, Netherlands, New Zealand, Peru, Spain, Switzerland, Taiwan, Thailand, United Kingdom, United States |
|
Conditions
The disease, disorder, syndrome, illness, or injury that is being studied. |
Glioblastoma, Small Cell Glioblastoma, Giant Cell Glioblastoma, Gliosarcoma, Glioblastoma With Oligodendroglial Component |
The purpose of this research study is to find out whether adding an experimental vaccine called rindopepimut (also known as CDX-110) to the commonly used chemotherapy drug temozolomide can help improve the life expectancy of patients with newly diagnosed, resected EGFRvIII positive glioblastoma. The duration of participation in this study may be up to 5 years. After you are screened and enrolled in the study, you will be administered temozolomide and either rindopepimut/GM-CSF or KLH until either disease progression or intolerance to the medications. If your tumor progresses while on this study, your doctor may treat you with other therapies that are not part of the study.
Arms
Experimental: Rindopepimut/GM-CSF plus Temozolomide
Active Comparator: KLH plus Temozolomide
Interventions
Drug: - Rindopepimut (CDX-110) with GM-CSF
Two intradermal injections two weeks apart, followed by monthly injections until tumor progression or intolerance. Each dose will be 0.8 mL containing approximately 500 mcg CDX-110 and 150 mcg GM CSF.
Drug: - Temozolomide
150 to 200 mg/m2 for 5 days during each 28-day cycle for a minimum of six cycles or a maximum of 12 cycles, or until intolerance or progression.
Drug: - KLH
Two intradermal injections two weeks apart, followed by monthly injections until tumor progression or intolerance. Each dose will be 0.8mL containing approximately 100mcg of KLH.
Contact a Trial Team
If you are interested in learning more about this trial, find the trial site nearest to your location and contact the site coordinator via email or phone. We also strongly recommend that you consult with your healthcare provider about the trials that may interest you and refer to our terms of service below.
Status
Address
University of Alabama at Birmingham
Birmingham, Alabama, 35294
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University of South Alabama Mitchell Cancer Institute
Mobile, Alabama, 36604
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Address
Barrow Neurological Institute at St. Joseph's Hospital and Medical Center
Phoenix, Arizona, 85013
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Address
University of Arizona Health Network
Tucson, Arizona, 85724
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Address
University of Arkansas for Medical Sciences
Little Rock, Arkansas, 72205
Status
Address
City of Hope Cancer Center
Duarte, California, 91010
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Address
UC San Diego Moores Cancer Center
La Jolla, California, 92093
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Address
USC Norris Comprehensive Cancer Center
Los Angeles, California, 90033
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Address
Chao Family Comprehensive Cancer Center
Orange, California, 92868
Status
Address
Kaiser Permanente, Redwood City Medical Center
Redwood City, California, 94063
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Address
University of California, Davis
Sacramento, California, 95817
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University of California, San Francisco
San Francisco, California, 94143
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Stanford Cancer Institute, Stanford University
Stanford, California, 94305
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Address
Hartford Hospital
Hartford, Connecticut, 06102
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Address
Yale University Medical Center
New Haven, Connecticut, 06520
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Address
Christiana Care Health Services
Newark, Delaware, 19713
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Address
University of Florida
Gainesville, Florida, 32611
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Address
Mount Sinai Medical Center, Comprehensive Cancer Center
Miami Beach, Florida, 33140
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Address
MD Anderson Cancer Center Orlando
Orlando, Florida, 32806
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Address
Tampa General Hospital
Tampa, Florida, 33606
Status
Address
Atlanta Cancer Care
Atlanta, Georgia, 30005
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Address
Winship Cancer Institute, Emory University School of Medicine
Atlanta, Georgia, 30322
Status
Address
Georgia Regents University
Augusta, Georgia, 30912
Status
Address
Kaiser Permanente Hawaii Moanalua Medical Center
Honolulu, Hawaii, 96819
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Address
Northwestern University Robert H. Lurie Comprehensive Cancer Center
Chicago, Illinois, 60611
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Address
Rush University Medical Center
Chicago, Illinois, 60612
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Address
University of Chicago
Chicago, Illinois, 60637
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Address
North Shore University Health System
Evanston, Illinois, 60201
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Address
Loyola University Medical Center
Maywood, Illinois, 60153
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Address
Covenant Clinic / Iowa Spine and Brain Institute
Waterloo, Iowa, 50702
Status
Address
University of Kentucky
Lexington, Kentucky, 40536-0093
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Address
Norton Cancer Institute
Louisville, Kentucky, 40202
Status
Address
Mary Bird Perkins Cancer Center
Baton Rouge, Louisiana, 70809
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Address
LSU Health Sciences Center, Feist-Weiller Cancer Center
Shreveport, Louisiana, 71103
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Address
Anne Arundel Medical Center
Annapolis, Maryland, 21401
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Address
Johns Hopkins University School of Medicine
Baltimore, Maryland, 21231
Status
Address
Center for Cancer and Blood Disorders, PC
Bethesda, Maryland, 20817
Status
Address
Dana-Farber Cancer Institute and Mass General Hospital
Boston, Massachusetts, 02115
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Address
Dana-Farber Cancer Institute
Boston, Massachusetts, 02215
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Address
University of Massachusetts Memorial Medical Center
Worcester, Massachusetts, 01655
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Address
University of Michigan Health System
Ann Arbor, Michigan, 48109
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Address
Edward W. Sparrow Hospital Association - Sparrow Regional Cancer Center
Lansing, Michigan, 48912
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Address
St. Mary's of Michigan Medical Center/Field Neurosciences Institute
Saginaw, Michigan, 48604
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Address
Allina Health, Abbott Northwestern Hospital, John Nasseff Neuroscience Institute
Minneapolis, Minnesota, 55407
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Address
Ellis Fischel Cancer Center
Columbia, Missouri, 65203
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Address
Washington University in St. Louis
Saint Louis, Missouri, 63110
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Southeast Nebraska Cancer Center
Lincoln, Nebraska, 68510
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Address
Dartmouth Hitchcock Medical Center
Lebanon, New Hampshire, 03756
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Address
New Jersey Neuroscience Institute, JFK Medical Center
Edison, New Jersey, 08818
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Address
John Theurer Cancer Center at Hackensack University Medical Center
Hackensack, New Jersey, 07601
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Address
Monmouth Medical Center
Long Branch, New Jersey, 07740
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Address
Dent Neurosciences Research Institute
Amherst, New York, 14226
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Montefiore Medical Center
Bronx, New York, 10467
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Address
New York Methodist Hospital
Brooklyn, New York, 11215
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Address
The Long Island Brain Tumor Center at Neurology Surgery, P.C.
Great Neck, New York, 11021
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Address
North Shore University Hospital
Manhasset, New York, 11030-3186
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Address
Columbia University Medical Center - The Neurologic Institute of New York
New York, New York, 10032
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Address
Weill Cornell Medical College
New York, New York, 10065
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Address
University of Rochester Medical Center
Rochester, New York, 14642
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Address
SUNY Upstate Medical University
Syracuse, New York, 13210
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Address
Brain and Spine Surgeons of New York
White Plains, New York, 10604
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Address
The Preston Robert Tisch Brain Tumor Center at Duke University Medical Center
Durham, North Carolina, 27710
Status
Address
Wake Forest Baptist Health
Winston-Salem, North Carolina, 27157
Status
Address
University of Cincinnati Cancer Institute
Cincinnati, Ohio, 45267
Status
Address
University Hospitals, Case Medical Center (Cleveland)
Cleveland, Ohio, 44106
Status
Address
Cleveland Clinic Foundation
Cleveland, Ohio, 44195
Status
Address
Ohio State University
Columbus, Ohio, 43210
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Address
Providence Portland Medical Center, Oncology & Hematology Care
Portland, Oregon, 97213
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Address
Pacific Neurosurgical
Portland, Oregon, 97227
Status
Address
Lehigh Valley Physician Group-Hematology-Oncology Associates
Allentown, Pennsylvania, 18103
Status
Address
University of Pennsylvania
Philadelphia, Pennsylvania, 19104
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Address
Temple University Hospital
Philadelphia, Pennsylvania, 19140
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Address
West Penn. Allegheny Health System
Pittsburgh, Pennsylvania, 15212
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Address
University of Pittsburgh Cancer Institute
Pittsburgh, Pennsylvania, 15232
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Address
Medical University of South Carolina - Department of Neuroscience
Charleston, South Carolina, 29425
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Address
University of Tennessee Medical Center - Knoxville
Knoxville, Tennessee, 37920
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Address
Sarah Cannon Research Institute
Nashville, Tennessee, 37203
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Address
Vanderbilt-Ingram Cancer Center
Nashville, Tennessee, 37232
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Address
Texas Oncology Midtwon
Austin, Texas, 78705
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Address
Baylor Research Institute
Dallas, Texas, 75246
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Address
The Methodist Neurological Institute
Houston, Texas, 77030
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University of Utah Department of Neurosurgery
Salt Lake City, Utah, 84112
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Address
Fletcher Allen Health Care
Burlington, Vermont, 05405
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Address
University of Virginia Healthcare System
Charlottesville, Virginia, 22908
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Address
Swedish Neuroscience Institute
Seattle, Washington, 98122
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Address
University of Washington Medical Center
Seattle, Washington, 98195
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Address
University of Wisconsin Paul P Carbone Comprehensive Cancer Center
Madison, Wisconsin, 53792
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Address
Medical College of Wisconsin
Milwaukee, Wisconsin, 53226
International Sites
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Prince of Wales Hospital
Randwick, New South Wales, 2031
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Address
Royal North Shore Hospital
St Leonards, New South Wales, 2605
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Address
The Crown Princess Mary Cancer Centre, Westmead Hospital
Westmead, New South Wales, 2145
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Address
Royal Brisbane and Women's Hospital
Herston, Queensland, 4029
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Address
Mater Adult Hospital, Mater Misericordiae Health Services Brisbane Limited
South Brisbane, Queensland, 4101
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Address
Royal Adelaide Hospital
Adelaide, South Australia, 5000
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Address
Calvary North Adelaide Hospital
North Adelaide, South Australia, 5006
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Address
Royal Hobart Hospital
Hobart, Tasmania, 7000
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Address
Launceston General Hospital
Launceston, Tasmania, 7250
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Monash Medical Centre
Clayton, Victoria, 3199
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Austin Health
Heidelberg, Victoria, 3084
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Address
Epworth Healthcare
Richmond, Victoria, 3121
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Sir Charles Gairdner Hospital
Nedlands, Western Australia, 06008
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Liverpool Hospital
Liverpool, , 2107
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Address
Medical University Innsbruck, Dept of Neurology, Anichstrabe 35
Innsbruck, , 6020
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Address
Medizinische Universität Wien, Innere Medizin I, Onkologie
Vienna, , 1090
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Address
Universitair Ziekenhuis Antwerpen
Edegem, Antwerp, 2650
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Address
ZNA Middelheim
Antwerpen, , B-2020
Status
Address
Ghent University Hospital
Ghent, , 9000
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Address
Hospital Mae de Deus-Centro de Pesquisa em Oncologia Clinica
Porto Alegre, Rio Grande Do Sul, 90840-440
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Centro de Pesquisas Clinicas da Fundação Dr Amaral Carvalho
Jaú, São Paulo, 17210-120
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Address
Fundação Faculdade Regional de Medicina de de São José do Rio Preto - Hospital de Base
São José do Rio Preto, São Paulo, 15090-000
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Instituto Nacional do Cancer (INCA)
Rio de Janeiro, , 20231-050
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Hospital Albert Einstein
Sao Paulo, , 05652-900
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Instituto do Câncer do Estado de São Paulo - ICESP
São Paulo, , 01246-000
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Real e Benemerita Associação Portuguesa de Beneficiência/ Hospital São José
São Paulo, , 01321-001
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Hospital A C Camargo
São Paulo, , 01509-900
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Address
Foothills Hospital Medical Centre
Calgary, Alberta, T3J 5N6
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Address
British Columbia Cancer Agency, Vancouver Clinic
Vancouver, British Columbia, V5Z 4E6
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Address
BC Cancer Agency - Vancouver Island Centre
Victoria, British Columbia, V8X 4V6
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Address
University of Manitoba-Cancer Care Manitoba
Winnipeg, Manitoba, R3E0V9
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Address
QEII Health Sciences Centre
Halifax, Nova Scotia, B3H 1V7
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Address
Juravinski Cancer Centre
Hamilton, Ontario, L8V 5C2
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Address
London Regional Cancer Program, London Health Sciences Centre
London, Ontario, N6A 4L6
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Ottawa Hospital, Regional Cancer Centre
Ottawa, Ontario, K1H 8L6
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Address
Sunnybrook Health Sciences Centre
Toronto, Ontario, M4N3M5
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Address
Centre Hospitalier de l'Universite de Montreal (CHUM) - Hopital Notre-Dame
Montreal, Quebec, H2L 4M1
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Address
Montreal Neurological Institute and Hospital
Montreal, Quebec, H3A 2B4
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Address
CHUS Hôpital Fleurimont
Shenbrooke, Quebec, J1H5N4
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Address
CHUQ L'Hotel Dieu de Qujebec
Quebec, , G1R 2J6
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Fundacion Santa Fe
Bogota, Bogota D.C, 000
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Address
Hospital Ceske Budejovice
Ceske Budejovice, , 370 01
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Address
Umiversity Hospital (Fakultni Nemocnice)
Prague, , 150 06
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Address
Hospital Na Homolce
Prague, , 150 30
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Address
Multiscan s.r.o.
Praha 5, , 155-00
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Address
Masaryk´s Hospital Usti nad Labem
Usti nad Labem, , 401-13
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Address
Institut de Cancerologie de I'Quest-Paul Papin
Angers, , 49933
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Address
Institute Bergonie
Bordeaux, , 33076
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Centre Leon Berard de Lyon
Lyon, , 69373
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Address
ICM Val d'Aurel Montpellier
Montpellier, , 342298
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Address
Institut de Cancerologie de L'Quest-Center Rane Gauducheau
Nantes, , 44805
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Address
Service de Neurologie-GH
Paris, , 75013
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Centre Eugene Marquis
Rennes, , 35042
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Address
Institut de Cancerologie de l'ouest-Center Rene Gauducheau
St Herblain, , 44805
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Address
Institut Gustave Roussy
Villejuif, , 94805
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Address
Klinik und Poliklinik fur Neurologie der Universitat Regensburg
Regensburg, Bavaria, 93053
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Address
Strahlenklinik Universitatsklinikum Erlangen
Erlangen, , D-91054
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Address
Dr. Senchkenbergisches Institut fur Neuroonkologie
Frankfurt, , D-60528
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Address
University Hospital Hamburg Kopf und Neurozentrum
Hamburg, , 20246
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Address
Universitaetsklinikum Heidelberg, Neurologische Klinik, IM Neuenheimer Feld 672
Heidelberg, , 69120
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Address
University Medical Centre
Kiel, , 24105
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Address
Universitaetsklinikum Muenster
Muenster, , 48149
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Address
LMU Munich
Munich, , D-81377
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Address
NNA
Athens, Attiki, 11521
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Address
"HYGEIA" Hospital
Marousi, District Of Attica, 151 23
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Address
Országos Onkológiai Intézet Sugárterápiás Osztály
Budapest, , 1122
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Address
Debreceni Egyetem Orvos- és Egészségtudományi Centrum Onkológiai Intézet
Debrecen, , 4032
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Address
Borsod-Abaúj-Zemplén Megyei Kórház és Egyetemi Oktató Kórház, Sugárterápiás Osztály
Miskolc, , 3526
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Address
Pécsi Tudományegyetem Általános Orvostudományi Kar
Pécs, , 7624
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Address
Szegedi Tudományegyetem Onkoterápiás Klinika
Szeged, , 6720
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Address
Vas Megyei Markusovszky Lajos Általános Rehabilitációs és Gyógyfürdő Kórház, Egyetemi Oktatókórház Nonprofit Zrt
Szombathely, , 9700
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Address
City Cancer Centre, Vijayawada
Vijayawada, Andhra Pradesh, 520002
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Address
HCG - Bangalore Institute of Oncology, Bangalore
Bengaluru, Karnataka, 560027
Status
Address
Amrita Institute of Medical Sciences and Research Centre, Kochi
Kochi, Kerala, 682 026
Status
Address
Sree Chitra Tirunal Institute for Medical Sciences & Technology, Thiruvananthapuram
Thiruvananthapuram, Kerala, 695 011
Status
Address
Marathwada Regional Cancer Centre and Research Institute - Government
Aurangabad, Maharashtra, 431001
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Address
Kokilaben Dhirubhai Ambani Hospital and Medical Research Institute
Andheri-West, Mumbai, 400 053
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Address
Tata Memorial Hospital , Mumbai
Parel, Mumbai, 400012
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Address
Indraprastha Apollo Hospital, New Delhi
Jasola Viha, New Delhi, 110076
Status
Address
Sahyadri Hospitals Limited
Erandauame, Pune, 411004
Status
Address
Dr. Rai Memorial Medical Centre, Chennai
Chennai, Tamil Nadu, 600018
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Address
HCG Shanti Mukand Hospital - Curie Cancer Centre, Delhi
Delhi, , 110092
Status
Address
Soroka University M.C.
Beer-Sheva, , 84101
Status
Address
Rambam Health Care Campus
Haifa, , 3109601
Status
Address
Hadassah Medical Center
Jerusalem, , 91120
Status
Address
SHEBA Medical Center
Tel Hashomer, , 52126
Status
Address
Tel-Aviv Sourasky Medical Center
Tel-Aviv, , 64239
Status
Address
UO Oncologie Medica Dipartimento Oncologico
Bologna, , 40139
Status
Address
Fondazione IRCCS Instituto Neurologico Carlo Besta
Milano, , 20133
Status
Address
Sacred Heart Catholic University
Rome, , 00168
Status
Address
Universita e AO Citta delia Scienza, Universita Di Torino
Torino, , 10126
Status
Address
Grupo Médico Camino S.C.
Mexico, D.F, 03310
Status
Address
Hospital Civil de Guadalajara "Fray Antonio Alcalde"
Guadalajara, Jalisco, 34000
Status
Address
Ensayos Clínicos y Medicina de Alta Especialidad, S.C.
Culiacán, Sinaloa, 80020
Status
Address
Servicios Medicos de Investigacion Clinica Sc
Durango, , 34000
Status
Address
Hospital Central "Ignacio Morones Prieto"
San Luis Potosí, , 78240
Status
Address
Medisch Centrum Haaglanden
The Hague, Zuid Holland, 2512 VA
Status
Address
VUMC
Amsterdam, , 1081HV
Status
Address
Radboud University Nijmegen Medical Center
Nijmegen, , 6525 GA
Status
Address
Christchurch Hospital
Christchurch Central, Christchurch, 8011
Status
Address
Palmerston North Hospital
Roslyn, Palmerston North, 4414
Status
Address
Waikato Hospital, Regional Cancer Centre
Hamilton, Waikato District, 3240
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Address
Waikato Hospital, Regional Cancer Center
Hamilton, Waikato Distric, 3240
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Address
Hospital Almanzor Aguinaga Asenjo
Chiclayo, ,
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Address
Instituto Oncologico Miraflores
Lima, , Lima 18
Status
Address
Clinica Anglo Americana
Lima, , Lima 27
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Address
Clinica Ricardo Palma
Lima, , Lima 27
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Address
Oncosalud
Lima, , Lima 41
Status
Address
Institut Catala d Oncologia
LaHospitalet De Lubregat, Catalonia, 08908
Status
Address
Dra. Sonia Del Barco Berron, ICO Girona Avda,
Franca, Girona, 17007
Status
Address
Hospital Clinic
Barcelona, , 8036
Status
Address
ICO Badalona-Hospital Germans Trias i Pujol
Barcelonia, , 08916
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Address
Hospital 12 de Octubre
Madrid, , 28041
Status
Address
Kantonsspital Aarau Medizinische Onkologie Tellstrasse
Aarau, AG, 5001
Status
Address
CHUV, Centre Hospitalier Universitaire Vaudois
Lausanne, VD, 1011
Status
Address
Oncology Institute of Southern Switzerland (IOSI)
Bellinzona, , 6500
Status
Address
Inselspital, Universitatsspital Bern, Universitatsklinik fur Medizinische Onkologie, Freiburgstrasse
Bern, , 3010
Status
Address
Hopitaux Universitaires de Geneve-HUG-Centre d'Oncologie
Geneva, , 1211
Status
Address
Brain Tumor Center, University Hospital Zurich
Zurich, , 8091
Status
Address
National Cheng Kung University Hospital
Tainan City, Bei District, 704
Status
Address
Kaohsiung Chang Gung Memorial Hospital
Kaohsiung, , 83301
Status
Address
Chang Gung Memorial Hospital Linkou Branch
Taichung, , 40705
Status
Address
Taichung Veterans General Hospital
Taichung, , 40705
Status
Address
Chi Mei Medical Center
Tainan City - Yongkang District, , 710
Status
Address
Tri-Service General Hospital
Taipei city - Neihu District, , 00114
Status
Address
Siriraj Hospital
Bangkoknoi, Bangkok, 10700
Status
Address
King Chulalongkorn Memorial Hospital
Patumwan, Bankok, 10330
Status
Address
Maharaj Nakorn Chiang Mai Hospital
Amphoe Muang, Chiang Mai, 50200
Status
Address
Songkhlanagarind Hospital
Hat Yai, Songkla, 90110
Status
Address
Royal Marsden NHS Foundation Trust
Sutton, Surrey, SM2 5PT
Status
Address
The Bristol Haematology and Oncology Centre
Bristol, , BS2 8ED
Status
Address
Edinburgh Cancer Centre Western General Hospital
Edinburgh, , EH4 2XU
Status
Address
Beatson West of Scotland Cancer Centrel
Glasgow, , G12 0NY
Status
Address
Guy's and St Thomas' NHS, Westminister Bridge Road
London, , SE17EH
Status
Address
Nottingham City Hospital
Nottingham, , NG5 1PB
